English

Alternative forms

• great pox
• Great Pox

Noun

great-pox ‎(uncountable)

1. (obsolete) syphilis
   • 1898, Thomas Stevenson, A treatise on hygiene and public health, volume 2, page 890:

     Putting aside passages which might possibly apply to great-pox, smallpox was evidently well known to Shakespeare and his contemporaries.