English

Verb

deimmortalize ‎(third-person singular simple present deimmortalizes, present participle deimmortalizing, simple past and past participle deimmortalized)

1. (biology) To make a cell subject to normal apoptosis
   • 2015 July 15, “TrAmplification of Human Dental Follicle Cells by piggyBac Transposon - Mediated Reversible Immortalization System”, in PLOS ONE, DOI:10.1371/journal.pone.0130937:

     After SV40 T-Ag was removed to deimmortalize the cells, telomerase activity was reduced to its original level before immortalization and decreased with passages just the same as primary DFCs. These results suggest that piggyBac immortalization system could be a potential strategy to amplify primary cells, which is critical for regenerative research and further clinical application.