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Definition 2024


dicyclohexylcarbodiimide

dicyclohexylcarbodiimide

English

Noun

dicyclohexylcarbodiimide (countable and uncountable, plural dicyclohexylcarbodiimides)

  1. (organic chemistry) The di-cyclohexyl derivative of carbodiimide that is used in peptide synthesis
    • 2015 June 13, Seryoung Kim et al., “Characterization of the l-alanine exporter AlaE of Escherichia coli and its potential role in protecting cells from a toxic-level accumulation of l-alanine and its derivatives”, in MicrobiologyOpen, volume 4, DOI:10.1002/mbo3.269:
      The reaction was initiated by adding a solution containing 50 mmol/L potassium phosphate (pH 7.0), 5 mmol/L MgSO 4 and carbonyl cyanide m -chlorophenylhydrazone (CCCP, final 20  μ mol/L) or dicyclohexylcarbodiimide (DCCD, final 50  μ mol/L), and [ 3 H] l -alanine (38 Ci mmol −1 , Moravek Biochemical, Brea, CA, USA; final, 0.54  μ mol/L).