(idiomatic,vulgar) to exploit somebody in a way which results in an advantage to oneself, at the cost of the other party gaining a considerable disadvantage.
He really fucked me over when he sold me that car for $3,000.
But not Huma. She quickly returned to Hillary’s side. Daniel Halper, online editor at the conservative Weekly Standard and the author of Clinton, Inc., an unflattering portrait of the Clintons, theorizes Huma had little choice after the second sexting fiasco but to stick with Hillary. “She started sort of easing her way out,” he says. “It would have helped if she was the First Lady of New York and would’ve had her own gig going, but, of course, her husband completely fucked her over. But, at that point, there was no way for her to exit gracefully.”