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Definition 2024


gliosis

gliosis

English

Noun

gliosis (countable and uncountable, plural glioses)

  1. A proliferation of astrocytes in damaged areas of the central nervous system. This proliferation usually leads to the formation of a glial scar.
    • 2001 November 23, Dorothee Chabas et al., “The Influence of the Proinflammatory Cytokine, Osteopontin, on Autoimmune Demyelinating Disease”, in Science, volume 294, number 5547, DOI:10.1126/science.1062960, pages 1731-1735:
      Material for the second MS library (herein MS2) came from a pool of tissues from two patients, one with acute, active lesions and widespread inflammatory involvement in the white matter, and the other with chronic, "silent" lesions, with gliosis, but without evidence of a lymphocytic infiltrate.