English

Structure diagram of isatin

Noun

isatin ‎(plural isatins)

1. (organic chemistry) The indole derivative 1H-indole-2,3-dione, used in the synthesis of dyes.
   • 1993, Vivette Glover, Merton Sandler, Tribulin and Isatin: An Update, Hajime Yasuhara, S. H. Parvez (editors), Monoamine Oxidase: Basic And Clinical Aspects, page 68,

     This finding suggests that the gut flora (absent, of course, in germ free animals) are responsible for the generation of most urinary isatin, but that the tissue material derives from a different source.

   • 2007, Shang-Tian Yang, Xiaoguang Liu, Yali Zhang, Chapter 4: Metabolic Engineering — Applications, Methods, and Challenges, Shang-Tian Yang (editor), Bioprocessing for Value-Added Products from Renewable Resources, page 81,

     One problem in large scale denim dyeing processes using biologically produced indigo is the undesirable red cast caused by indirubin, which is a structural isomer of indigo formed from indoxyl and isatin, a byproduct of the spontaneous oxidation reaction that converts indoxyl to indigo.

   • 2014, Kiran Gangarapu, Development of Isatin as CNS Agents: Anticonvulsant activity, Anchor Academic Publishing, page 7,

     Isatin reacts with formaldehyde and a variety of amines in the Mannich reaction to give their respective bases (10), in the absence of an amine, isatin and substituted isatin with formaldehyde give hydroxymethyl isatins (11).

Translations

Derived terms

• isatic acid, isatinic acid