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Definition 2024


naltrindole

naltrindole

English

Noun

naltrindole (uncountable)

  1. A highly potent and selective delta opioid receptor antagonist used in biomedical research.
    • 2015 December 24, “Berberine Improves Intestinal Motility and Visceral Pain in the Mouse Models Mimicking Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D) Symptoms in an Opioid-Receptor Dependent Manner”, in PLOS ONE, DOI:10.1371/journal.pone.0145556:
      The effect of berberine(2 mg/kg, i.p.) was blocked by the i.p. administration of the non-selective opioid receptor antagonist naloxone, the selective MOR antagonist β-funaltrexamine and DOR antagonist naltrindole, but not KOR antagonist nor-binaltorphimine.