English

Adjective

prehepatic ‎(not comparable)

1. (biochemistry) Before the metabolic effect of the liver
   • 2015 June 12, Jeanne Mendell et al., “The Effect of Rifampin on the Pharmacokinetics of Edoxaban in Healthy Adults”, in Clinical Drug Investigation, volume 35, DOI:10.1007/s40261-015-0298-2:

     Administration of intravenous edoxaban with and without rifampin may have differentiated the prehepatic versus hepatic effects of rifampin on parent and metabolite exposure.