English

Noun

preprotein ‎(plural preproteins)

1. (biochemistry) A polypeptide chain that is in the process of growing into a protein by the addition of successive amino acid moieties
   • 2015 July 8, Ozra Tabatabaei-Malazy, Bagher Larijani, Mohammad Abdollahi, “Targeting metabolic disorders by natural products”, in Journal of Diabetes and Metabolic Disorders, volume 14, DOI:10.1186/s40200-015-0184-8:

     The strategies have been focused on production of stronger statins, MTP inhibitors such as Lomitapide, ACAT2 inhibitors, cholesteryl ester transfer protein (CETP) inhibitors such as Torcetrapib, Anacetrapib, Evacetrapib, and Dalcetrapib, antioxidants, squalene synthase inhibitors, preprotein convertase subtilisin kexin-9 inhibitors (PCSK9) such as Regeneron®, selective thyroid hormone mimetics such as Sobetirome as a β-receptor agonist, combination form of PPAR-α and γ agonists (Aleglitazar), PPAR-δ agonists (GW501516), and Apo A-I agonists (CSL-112) [ 116 , 118 ].