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Definition 2025
shugoshin
shugoshin
English
Noun
shugoshin (plural shugoshins)
- (biochemistry) Any of a family of proteins that play a role in the centromeric protection of cohesin
- 2015 May 13, Chey Loveday et al., “Mutations in the PP2A regulatory subunit B family genes PPP2R5B, PPP2R5C and PPP2R5D cause human overgrowth”, in Human Molecular Genetics, volume 24, DOI: :
- The shugoshin Sgo1 homodimer and inhibitor toxin microcystin peptide have been omitted for clarity.