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Definition 2024


thiocolchicine

thiocolchicine

English

Noun

thiocolchicine (plural thiocolchicines)

  1. (organic chemistry) Any thio derivative of colchicine, but especially the tubulin synthesis inhibitor 10-thiocolchicine
    • 2015 September 11, “A Novel Microtubule-Disrupting Agent Induces Endoplasmic Reticular Stress-Mediated Cell Death in Human Hepatocellular Carcinoma Cells”, in PLOS ONE, DOI:10.1371/journal.pone.0136340:
      However, owing to their high toxicities, colchicine and thiocolchicine are still in preclinical trials to determine their potential anti-tumor activity.