English

Molecular structure of tolbutamide

Noun

tolbutamide ‎(countable and uncountable, plural tolbutamides)

1. A drug that blocks potassium channels, used in the treatment of diabetes.
   • 2009 March 27, Ken-ichi Takeuchi et al., “Changes in Temperature Preferences and Energy Homeostasis in Dystroglycan Mutants”, in Science, volume 323, number 5922, DOI:10.1126/science.1165712, pages 1740-1743:

     The cryophilic phenotype of the atu mutant was alleviated to some extent by administering rotenone, a pharmacological inhibitor of oxidative phosphorylation, but not tolbutamide, a sulphonylurea that stimulates metabolic rate by raising the lymphatic concentration of glucose.

Hypernyms

• sulfonylurea

See also

• tolbutamide on Wikipedia.Wikipedia