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Webster 1913 Edition

adv.

In a manner, or to a degree, that precludes remedy, cure, or correction.

adv.

In a manner or degree that precludes remedy, cure or correction.

irremediably ‎(comparative more irremediably, superlative most irremediably)

In a manner, or to a degree, that precludes remedy, cure, or correction; in an irremediable way.

in an irremediable way

irremediably in The Century Dictionary, The Century Co., New York, 1911
irremediably in Webster’s Revised Unabridged Dictionary, G. & C. Merriam, 1913