Definify.com
Webster 1913 Edition
Depressant
De-press′ant
,Noun.
 (Med.) 
An agent or remedy which lowers the vital powers. 
Definition 2025
depressant
depressant
English
Noun
depressant (countable and uncountable, plural depressants)
-  (pharmacology) A pharmacological substance which decreases neuronal or physiological activity.
- Alcohol acts first as a stimulant and then as a depressant.
 
 - (mining) An agent that inhibits the flotation of a mineral or minerals.
 
Adjective
depressant (comparative more depressant, superlative most depressant)
- Acting as a depressant.